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HelpAspirin Screening Test
Additional Codes
LAB5413
Methodology
Turbidimetric Based Optical Detection System
Note: The assay detects aspirin inhibition of platelet aggregation due to irreversible acetylation of cyclo-oxygenase-1 and reduced thromboxane A2 synthesis.
Literature Reference:
Package insert: VerifyNow Aspirin, 14314.H. Accumetrics, Inc, 04/27/2009.
Specimen Requirements
Call MBMC Hematology Laboratory at 314-996-5809 to obtain 2, 2-mL Griener Bio-One Vacuette tubes.
Specimen Type: Sodium citrate plasma
Container/Tube: 2-mL Griener Bio-One Vacuette tubes
Alternate Tube(s): None
Specimen Volume: 2 Full tubes
Collection Instructions: Do not centrifuge. Clotted blood or an insufficient specimen is not acceptable.
Additional Information: Avoid hemolysis and heparin contamination of specimen.
Collection Procedure:
Attention to collection procedure is necessary to avoid inaccurate results, collect as follows:
1. Draw a discard tube (volume depends on type of venous access).
2. Draw 2 Griener blue-top tubes. Do not overfill or under fill.
3. Forward promptly at ambient temperature. Do not send Greiner blue-top tube through the pneumatic tube system.
Day(s) Test Set Up
Monday through Sunday
Turnaround Time:
STAT: not available
Routine: 2 hours
Reference Values
≤550 ARU (Aspirin Response Unit): Adequate inhibition of platelet aggregation.
Literature Reference:
Prabhakaran S, Wells KR, Lee VH, Flaherty CA, Lopes DK. Prevalence and risk factors for aspirin and clopidogrel resistance in cerebrovascular stenting. (Published November 7, 2007 as 10.317/ajnr.A0818, www.ajnr.org.)
Test Classification and CPT Coding
85576
Specimen Transport Temperature
Ambient
Stability
4 hours at ambient temperature