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Pancreatobiliary FISH

Performing Laboratory

ARUP Laboratory

Specimen Requirements

Collect:  Bile or pancreatic duct brushings, biliary stent, or fine needle aspirates of the pancreas in UroVysion FISH Collection Kit (ARUP Supply #41440) available online through eSupply using ARUP Connector contact Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection & Handling.

 

Specimen Preparation:  Place specimen in Cytolyt or PreservCyt fixative vial. If the specimen is a brushing, submit the brush in the fixative. Specimen should be placed in fixative vial immediately after collection.

NOTE:  Specimen source is required.

Specimen Transport Temperature

Storage/Transport Temperature:  Ambient or Refrigerated.

Unacceptable Conditions:  Frozen specimens. Unfixed specimens not collected in Cytolyt or PreservCyt fixative. Specimens submitted in expired collection vials.

Stability:  Ambient: 1 week from collection; Refrigerated: 1 week from collection; Frozen: Unacceptable

Day(s) Test Set Up

Perfomed:  Mon-Fri

TAT: Reported 4-12 days

Reference Values

Positive ≥5 cells with gains of two or more chromosomes are present
Equivocal Tetrasomy Cells present with tetrasomic or near tetrasomic signal patterns
Equivocal Trisomy ≥10 cells with gains of a single chromosome, (Trisomy 7 or Trisomy 3)
Negative < 5 abnormal cells are present

Test Classification and CPT Coding

88366