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HelpAcetylcholine Receptor Modulating Antibody
Additional Codes
LAB837
Clinical Significance
Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. Modulating Antibody to AChR causes weakness by inhibiting or modulating binding to the receptors.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
Methodology
Radiobinding Assay
Specimen Requirements
Specimen Type:Serum
Container/Tube: Red
Specimen Volume: 1 mL serum (1 Full tube)
Specimen Minimum Volume: 0.5 mL serum
Specimen Transport Temperature
Ambient - 14 days (preferred)
Refrigerated - 14 days
Frozen - 30 days
Day(s) Test Set Up
Set up: Sun, Tues, Thurs; Report available: 4-8 days
Reference Values
<32% Inhibition
Test Classification and CPT Coding
86043
Specimen Stability
Ambient - 14 days (preferred)
Refrigerated - 14 days
Frozen - 30 days
Limitations
Antibodies may not be found in congenital myasthenia.