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BCL6 3q27, NH-(Diffuse Large B-Cell Lymphoma, FL)

Additional Codes

LAB6814

Performing Laboratory

GenPath/Bio-Reference Laboratories, Inc.

Methodology

FISH

BCL6 3q27 is found in up to 35% of DLBCL and 6% to 14% of follicular lymphoma. FL with BCL6 translocation suggests a subgroup prone to early transformation to a more aggressive lymphoma (DLBCL).

Specimen Requirements

Specimen must arrive at GenPath within 24 hours of collection.

 

Specimen source is required.

 

Submit only 1 of the following specimens.

 

Specimen Type: Bone marrow

Container/Tube: Green top (heparin) or Lavender top (EDTA)

Specimen Volume: 0.5 mL

 

Specimen Type: Whole blood

Container/Tube: Green top (heparin) or Lavender top (EDTA)

Specimen Volume: 5 mL

 

Specimen Type: Fresh tissue

Container/Tube: Container with RPMI media

Specimen Volume: Adequate amount

 

Alternate

Specimen Type: Non-decalcified paraffin-embedded tissue block

Specimen Volume: Adequate amount

 

 

Causes for Specimen Rejection:

-No patient ID on specimen

-Patient ID on specimen and requisition doesn’t match

-Incorrect fixative (tube/solution)

-Specimen without GenPath/Bio-Reference requisition

-Frozen specimen

Specimen Transport Temperature

Refrigerate <24 hours/Ambient NO/Frozen NO

Day(s) Test Set Up

Monday through Saturday

Turnaround Time:

24 to 72 hours

Test Classification and CPT Coding

88377