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HelpPML/RARA, FISH-GenPath
Additional Codes
LAB7553
Performing Laboratory
GenPath/Bio-Reference Laboratories, Inc.
Methodology
FISH
Diagnostic for AML-M3. Detected in about 5% to 8% of AML patients. Treatment with acute promyelocytic leukemia all-trans retinoic acid (ATRA) and other chemotherapy agents, can induce maturation.Usually associated with a favorable response to chemotherapy.
Specimen Requirements
Specimen must arrive at GenPath within 24 hours of collection.
Specimen source is required.
Submit only 1 of the following specimens.
Specimen Type: Bone marrow
Container/Tube: Green top (Heparin) or Lavender top (EDTA)
Specimen Volume: 0.5 mL
Specimen Type: Whole blood
Container/Tube: Green top (Heparin) or Lavender top (EDTA)
Specimen Volume: 5 mL
Specimen Type: Fresh tissue
Container/Tube: Container with RPMI media
Specimen Volume: Adequate amount
Alternate
Specimen Type: Non-decalcified paraffin-embedded tissue block
Specimen Volume: Adequate amount
Causes for Specimen Rejection:
-No patient ID on specimen
-Patient ID on specimen and requisition doesn’t match
-Incorrect fixative (tube/solution)
-Specimen without GenPath/Bio-Reference requisition
-Frozen specimen
Specimen Transport Temperature
Refrigerate <24 hours/Ambient NO/Frozen NO
Day(s) Test Set Up
Monday through Saturday
Turnaround Time:
24 to 72 hours
Test Classification and CPT Coding
88374