BCR/ABL, t(9;22), Chronic Myelogenous Leukemia (CML) FISH
Additional Codes
LAB6816
Performing Laboratory
GenPath/Bio-Reference Laboratories, Inc.
Methodology
FISH
BCR/ABL, t(9;22) is diagnostic for CML and is also seen in a subset of ALL and AML. In adult ALL and AML, usually associated with an unfavorable response to chemotherapy.
Specimen Requirements
Specimen must arrive at GenPath within 24 hours of collection.
Specimen source is required.
Submit only 1 of the following specimens.
Specimen Type: Bone marrow
Container/Tube: Green top (heparin) or Lavender top (EDTA)
Specimen Volume: 1 mL
Specimen Type: Whole blood
Container/Tube: Green top (heparin) or Lavender top (EDTA)
Specimen Volume: 5 mL
Specimen Type: Fresh tissue
Container/Tube: Container with RPMI media
Specimen Volume: Adequate amount
Alternate
Specimen Type: Non-decalcified paraffin-embedded tissue block
Specimen Volume: Adequate amount
Causes for Specimen Rejection:
-No patient ID on specimen
-Patient ID on specimen and requisition doesn’t match
-Incorrect fixative (tube/solution)
-Specimen without GenPath/Bio-Reference requisition
-Frozen specimen
Specimen Transport Temperature
Refrigerate <24 hours/Ambient NO/Frozen NO
Day(s) Test Set Up
Monday through Saturday
Turnaround Time:
24 to 72 hours
Test Classification and CPT Coding
88374