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JAK-2 Exon 12 in Myeloproliferative Neoplasms (MPN) Mutation Analysis

Important Note

 JAK2 Exon 12 testing should be performed only after a negative JAK2 V617F result.

Additional Codes

 LAB20888

Performing Laboratory

GenPath/Bio-Reference Laboratories, Inc.

Methodology

Allele-Specific PCR and Sequencing

JAK2 exon 12 mutations help confirm polycythemia vera in MPN patients that are JAK2 V617F-negative.

Specimen Requirements

Specimen Type: Whole blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 5 mL

Specimen Transport Temperature

Ambient

Day(s) Test Set Up

Turnaround Time:

3 to 5 days

Test Classification and CPT Coding

81279