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GENERAL INFORMATION

SPECIMEN COLLECTION

PATIENT INFORMATION

LINKS

Mayo Medical Laboratories

Mayo Clinic Laboratories

19911 A→G Mutation Analysis

Additional Codes

LAB3513

Methodology

Capillary Electrophoresis • Fluorescence Detection • Polymerase Chain Reaction Amplification • Single Nucleotide Extension

Reference Range(s)

See Laboratory Report

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in: ACD solution A or B (yellow-top) tube, lithium heparin (green-top) tube or sodium heparin (green-top) tube

Minimum Volume

3 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Setup Schedule

Set up: Thur a.m.; Report available: 14 days

Reject Criteria

Received frozen

Clinical Significance

This test can be used to detect the 19911A→G polymorphism in the prothrombin (Factor II) gene which may modulate the risk of deep vein thrombosis in patients with the G20210A mutation

CPT Code

81400