Sign in →

Test Code IGF1 Insulin-Like Growth Factor 1 (IGF1), Blood

Additional Codes

LAB526

Performing Laboratory

St. Louis Children's Hospital

Specimen Requirements

Specimen Type: Blood

Container/Tube

Preferred: Mint green-top (lithium heparin) Vacutainer®.

Acceptable: Gold/Red SST Vacutainer® or Plain, red-top Vacutainer®.

Collection Volume: 2.0 mL (minimum 0.6 mL)

Patient Preparation: Sample should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours following the last biotin administration.

Sample Rejection:

Specimens that are grossly hemolyzed.
Mislabeled or unlabeled specimens.

Special Instructions: None

Interpretive

Reference Range:

Age: years

Male

Female

<2

10-200

10-200

2-3

10-250

10-250

3-4

20-250

20-250

4-5

30-250

30-250

5-6

40-250

40-250

6-7

50-275

45-250

7-8

50-300

45-300

8-9

60-350

50-350

9-10

70-400

60-400

10-11

70-450

70-500

11-12

80-500

90-600

12-13

85-550

100-650

13-14

90-600

110-700

14-15

95-620

115-750

15-16

100-650

120-700

16-17

100-650

120-600

17-18

100-600

120-500

18-20

90-500

100-400

20-22

80-400

80-350

23-25

65-350

70-320

26-30

60-330

65-300

31-35

55-300

60-280

36-40

50-300

55-250

41-45

45-275

50-250

46-50

40-250

45-230

51-55

35-250

40-210

56-60

35-230

35-200

≥61

30-200

30-200

 

 

 

Tanner Stage

 

 

I

80-250

80-320

II

100-450

120-450

III

250-500

250-550

IV

225-600

225-600

V

225-500

180-500

 

 

 

Assay calibrated to WHO 02/254 and instituted at SLCH 5/2018.

Current interpretive criteria established 5-10-2018.

References:

  1. Elecsys IGF-1 Package Insert 2017-10, V 1.0

  2. Mayo Medical Laboratories IGFMS entry (https://www.mayomedicallaboratories.com/test-catalog/Overview/62750) accessed 5-9-2018.

  3. Bidlingmaier M, Fredrich N Emen RT et al.  J Clin Endocrinol Metab 2014;99:1712-1721

Critical Values: None established

Limitations: Sample should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours following the last biotin administration.

Methodology: Sandwich principle

General Information

EPIC order name: Insulin Like Growth Factor (EPIC Test#LAB526)
Cerner order name: IGF1
CPT Codes: 84305
LOINC Value: In process
Synonyms: Somatomedin C; IGF1

Last Reviewed

November 2024

Logistics

Test Availability: Daily
Test set-up: Monday-Sunday
Cut-off time: None; performed as received.
Turnaround Time: Same day, results available 2 hours from receipt in lab
Lab Testing Section: Chemistry

Lab Dept

Core Lab

Additional Information

For SLCH Laboratory use only

Lab Processing instructions: Centrifuge specimen to separate. If specimen is collected in plain, red-top tube aliquot sample into a conical tube for testing (labeling aliquot tube as 'serum').

Processed Volume: 0.5 mL (minimum 0.3 mL) serum
Analyte Stability:

Ambient - unprocessed: 8 hours
PROCESSED

Ambient: 24 hours
Refrigerated: 48 hours
Frozen: 28 days
 
Notes: Will also accept Lavender-top (EDTA) plasma; making sure aliquot is labeled as "EDTA plasma"