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Thyroid Function Cascade

Additional Codes

LAB5725

Performing Laboratory

MBMC Main Laboratory

Methodology

Electro-Chemiluminescent Immunoassay (ECLIA)

 

Testing Algorithm

If the TSH result is outside of established reference range, a Free T4 will reflex with an additional charge.  If the Free T4 result is < 1.7 ng/dL  and the TSH is <0.3mcLUnits/mL, a Free T3 will reflex with an additional charge. 

Specimen Requirements

Specimen Type: Plasma
Container/Tube: Mint-green top (lithium heparin)
Specimen Volume: Full tube

Specimen Minimum Volume: 2.5 mL

Alternative Specimen Type: Serum

Alternative Container/Tube: Gold, Serum gel

Alternative Specimen Volume: Full tube

Specimen Transport Temperature

Ambient

Day(s) Test Set Up

Monday through Sunday
Turnaround Time:
STAT: 1 hour after receipt in laboratory
Routine: within 4 hours

Reference Values

TSH:

0-4 days:     1.00 - 25.00 uIU/mL

4-30 days:   0.50 - 10.00 uIU/mL

>30 days:    0.30 - 4.20 uIU/mL

 

TSH concentration may range up to 100 mcIUnits/mL due to surge of TSH production on the first day of life and then fall gradually to adult levels by one month of age.

 

Free T4:

0 minutes-4 days     1.00 - 3.00 ng/mL

4 days-30 days         0.80 - 2.20 ng/mL

30 days-150 years    0.90 - 1.70 ng/mL

 

Free T4 concentrations rise acutely to as high as 5.00 ng/dL on the first day of life following TSH surge and then decrease gradually to adult levels by one month of age.

Free T3:

2.00-4.40 pg/mL

Test Classification and CPT Coding

 

Test Classification:This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer’s instructions.
CPT Code:
84443-TSH

 

84439-Free T4, if appropriate

84481-Free T3, if appropriate