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Itraconazole Level 

Important Note

Centrifuge specimen to separate within 2 hours of collection. Aliquot serum into a conical tube.

Additional Codes

LAB7715

Performing Laboratory

St. Louis Children's Hospital Laboratory

Specimen Requirements

Container/Tube: Red Top

Specimen Volume: 2 mL

Collection Instructions: Spin down within 2 hours of draw

Specimen Minimum Volume: 0.5 mL

Sample Rejection:  Specimens collected in gel tubes

Specimen Transport Temperature

Refrigerated

Day(s) Test Set Up

Test set-up:  Monday, Wednesday, & Friday;  cut-off: 09:00 a.m.

Turnaround Time:  1-3 days

Reference Values

Itraconazole (trough)

 

localized infection:

>0.5 mcg/mL

 

systemic infection:

>1.0 mcg/mL

Hydroxyitraconazole

 

 

No therapeutic range established; activity and serum concentration are similar to parent drug.

Critical Value: Itraconazole+Hydroxyitraconazole (combined total) ≥ 10.0 mcg/mL

Test Classification and CPT Coding

This test was developed and its performance characteristics determined by St Louis Children's Hospital Laboratory in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code 80189