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Celiac Genetics

Additional Codes

LAB7834

Performing Laboratory

PROMETHEUS Laboratories Inc.

Methodology

PROMETHEUS Celiac Genetics analyzes a patient’s genetic profile for genes specifically associated with celiac disease. Advanced high-resolution DNA probe analysis of HLA-DQ haplotypes allow for disease risk stratification depending upon which HLA genes are detected. Also, testing can predict with a 95% to 100% negative predictive value (NPV) that the patient will not develop celiac disease if HLA-DQ2 and HLA-DQ8 haplotypes are not present.

Specimen Requirements

Specimen Type: Whole blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 5 mL

Specimen Transport Temperature

Ambient <7 days/Refrigerated <30 days OK

Day(s) Test Set Up

 

Turnaround Time:3 business days from date of receipt.

 

Reference Values

HLA-DQ2/DQ8: Not Detected (Allele frequency varies by ethnic population)

Test Classification and CPT Coding

81382 x2