Test Code LAB906 Pneumocystis (DFA)
Additional Codes
LAB906
Methodology
Direct Fluorescent Antigen (DFA)
Performing Laboratory
Barnes-Jewish Hospital Laboratory
Specimen Requirements
Acceptable Specimens:Bronchoalveolar lavage, bronchial washing, induced sputum: ≥2 mL in a leakproof screw-capped, sterile container
Unacceptable Specimens:
Expectorated sputum and tracheal aspirates. Tissue (Send tissue specimens to histopathology.)
Collection Procedure:
1. Aseptically collect ≥2 mL of specimen.
2. Place specimen in a leakproof screw-capped, sterile container.
3. Maintain sterility and forward promptly.
4. If transport is delayed, refrigerate specimen.
Note: Specimen source is required.
Specimen Transport Temperature
Ambient/Refrigerate if transport is delayed
Reference Values
The fluorescein-labeled monoclonal antibodies specifically stain cysts of Pneumocystis jirovecii (P. carinii). The test is very specific and has a reported sensitivity of 50% to 80% with induced sputum and 90% to 95% with bronchoalveolar lavage.
Literature Reference:
Cushion MT. Pneumocystis. In: Versalovic, James, Carroll, KC, Jorgensen JH, et al. Manual of clinical microbiology. 11th ed. Washington DC: American Society for Microbiology; 2015;2015-2026.
Day(s) Test Set Up
Monday through Sunday
Cut-off time: 0900
Turnaround Time:
STAT: not available
Routine: results available the day of testing
Test Classification and CPT Coding
87281
Additional Information
For BJH Laboratory Use Only
Minimum Volume:
0.5 mL in a leakproof screw-capped, sterile container
Laboratory Processing Instructions:
Test performed in BJH Microbiology.